ESCRTing Necroptosis

نویسندگان

  • Hongyan Guo
  • William J. Kaiser
چکیده

Necroptosis is a highly inflammatory form of programmed cell death that results from MLKL-mediated disruption of the cell membrane. In this issue of Cell, Gong et al. challenge the notion that MLKL activation is a point of no return by identifying mechanisms to counterbalance necroptosis, sustain plasma membrane integrity, and prolong cell viability.

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عنوان ژورنال:
  • Cell

دوره 169  شماره 

صفحات  -

تاریخ انتشار 2017